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What is ayahuasca?
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Purchase Ayahuasca is the Quechua word referring to a liquid produced by the slow decoction or admixture
of the Amazonian Banisteriopsis caapi vine – as well as to the vine itself – which contains harmine,
harmaline and tetrahydroharmine. It is traditionally used throughout the Northwestern Amazon,
originating from indigenous cultures that have used it for hundreds of years for medicinal and
ritual purposes. At the beginning of the last century, syncretic religions incorporating shamanic
worldviews into Christian rituals began to use ayahuasca. In the early 20th century, these
churches expanded into Amazonian urban centers (Labate, 2004) and, over the last thirty years,
globally (Labate & Jungaberle, 2011).

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Based on the intended use of the decoction or admixture of the vine called ayahuasca, each
Amazonian culture, shaman, healer, man or woman with experience using ayahuasca, adds
different plants to the brew with the objective of searching for a specific effect depending on the
disease to be healed or ritual to be performed. Ethnographic studies suggest that there are more
than 5,000 different ways to prepare ayahuasca, all using B. caapi as their base (Fericgla, 1997).
Some of these traditional recipes, considering both the indigenous cultures and the religions that
use ayahuasca as their sacrament (or “ayahuasca religions”), include adding leaves of the
Psychotria viridis bush, which contains DMT (N,N-Dimethyltryptamine), along with the B. caapi
vine (Schultes & Hofmann, 1992). Ayahuasca is currently being popularized as the combination of
B. caapi and P. viridis, likely because the international expansion of ayahuasca practices was
initiated by these churches (Sánchez & Bouso, 2015). Purchase Ayahuasca

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The precise historical beginning of ayahuasca use is unknown. Archaeological evidence has dated
the use of ayahuasca to more than 1,000 years (Miller et al., 2019). Among Amazonian ethnic
groups, the use of ayahuasca decoctions/admixtures that also contain plants with DMT seems to
be a more recent phenomenon (Brabec de Mori, 2011).
Ayahuasca is considered a sacred drink by innumerable indigenous Amazonian groups and a
medicine by mestizo healers in much of South America. The traditional and modern use of
ayahuasca extends from Panama to Bolivia, including Peru, Ecuador, Colombia, and Brazil –
countries in which its medicinal use is deeply present in urban centers (Luna, 1986, 2011). A
pioneering 1986 work that brought together all the scientific information on ayahuasca available at
that time found more than 400 bibliographical references on the ethnography of ayahuasca (Luna,
1986b), references to more than 70 different Amazonian ethnic groups where it was used
traditionally, and more than 40 vernacular names given to the decoction (Luna, 1986c). Ayahuasca
is currently being used as a medicine in ceremonies officiated by indigenous peoples, mestizos,
and diverse professionals who have learned to use it in its places of traditional origin (Labate &
Bouso, 2013; Labate & Cavnar, 2014a; Labate, Cavnar & Gearin, 2017; Labate et al., 2009; Luna,
2011).

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2. The legal status of ayahuasca
As noted above, ayahuasca is typically produced by the slow decoction/admixture of two plants –
B. caapi and P. viridis. The latter of these two plants contains DMT (N,N-dimethyltryptamine), a
tryptamine alkaloid listed in the 1971 Convention on Psychotropic Substances, and many
countries therefore also include it in their national legislation. Although DMT is listed in Schedule I
of the 1971 Convention (the most restrictive category), the International Narcotics Control Board
2
(INCB), a quasi-judicial control body for the implementation of the United Nations drug
conventions, has stated on several occasions that ayahuasca – as well as other psychoactive
plants – is not subject to international control.
In its 2010 Annual Report, the INCB stated that “although some active stimulant or hallucinogenic
ingredients contained in certain plants are controlled under the 1971 Convention, no plants are
currently controlled under that Convention or under the 1988 Convention. Preparations (e.g. 1
decoctions for oral use) made from plants containing those active ingredients are also not under
international control” (paragraph 284, INCB, 2010).
The alkaloids present in the B. caapi vine are also not subject to international control. In 2008,
ayahuasca was declared Cultural Patrimony of Peru, due to its ancestral use as a traditional
medicine (Instituto Nacional de Cultura, 2008) and its use for religious purposes is firmly
established and legalized in Brazil (Labate et al., 2009). The religious use of ayahuasca has been
permitted for some churches in the USA and Canada, and the churches in which ayahuasca is
considered a sacrament and is consumed for that purpose have expanded internationally into
numerous European, American, and Asian countries (Labate et al., 2009; Labate & Feeney, 2012;
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