Widespread drastic reduction of brain myelin content upon prolonged endurance exercise
Pedro Ramos-Cabrer cs 2023 doi https://doi.org/10.1101/2023.10.10.561303 (this article is a preprint, and has not been certified by peer review)
Recent evidence suggests:
myelin lipids may act as glial energy reserves when glucose is lacking, a hypothesis yet to be solidly
Hereby, we examined the effects of running a marathon on the myelin content by MRI.
Our findings:
marathon runners undergo widespread robust myelin decrease at completion of the effort.
This reduction involves white & gray matter, it includes
- primary motor & sensory cortical areas & pathways,
- the entire corpus callosum & internal capsule.
Myelin levels partially recover within 2 weeks after the marathon.
These results reveal:
myelin use & replenishment is an unprecedented form of metabolic plasticity, aimed to maintain brain function during extreme conditions.
Widespread drastic reduction of brain myelin content upon prolonged endurance exercise
Pedro Ramos-Cabrer cs 2023 doi https://doi.org/10.1101/2023.10.10.561303 (this article is a preprint, and has not been certified by peer review) Recent evidence suggests:
myelin lipids may act as glial energy reserves when glucose is lacking, a hypothesis yet to be solidly
yet to be proven :=}
Hereby, we examined the effects of running a marathon on the myelin content by MRI.
Our findings:
marathon runners undergo widespread robust myelin decrease at completion of the effort.
This reduction involves white & gray matter, it includes
- primary motor & sensory cortical areas & pathways,
- the entire corpus callosum & internal capsule.
Myelin levels partially recover within 2 weeks after the marathon.
These results reveal:
myelin use & replenishment is an unprecedented form of metabolic plasticity, aimed to maintain brain function during extreme conditions.
Marc Verhaegen wrote:
Myelin levels partially recover within 2 weeks after the marathon.
These results reveal:
myelin use & replenishment is an unprecedented form of metabolic plasticity, aimed to maintain brain function during extreme conditions.
yet to be proven :=}
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