Op zondag 23 april 2023 om 17:43:50 UTC+2 schreef JTEM is so reasonable:
DHA alone proves Aquatic Ape.
:-) I think so, but I'm not 100% sure:
does DHA automatically enlarge mammalian/primate brains??
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917688/
Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes
James V Pottala cs 2014 Neurology 82:435-442 doi 10.1212/WNL.0000000000000080
Were red blood cell (RBC) levels of marine omega-3 fatty acids (FAs) measured in the Women's Health Initiative Memory Study related to MRI brain volumes measured 8 yrs later?
RBC eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) & MRI brain volumes were assessed in 1111 postmenopausal women (WHIMS).
The endpoints were total brain volume & anatomical regions.
Linear mixed models included multiple imputations of FAs,
they were adjusted for hormone therapy, time since randomization, demographics, intra-cranial volume (CC) & cardio-vascular disease risk factors.
Results:
In fully adjusted models, a 1 SD greater RBC EPA + DHA (omega-3 index) level was correlated with 2.1 cm3 larger CC (p=.048).
DHA was marginally correlated (p=.063) with total CC, EPA was less so (p=.11).
There were no correlations between ischemic lesion volumes & EPA, DHA, EPA+DHA.
A 1 SD greater omega-3 index was correlated with greater hippocampal volume (50 mm3, p=.036) in fully adjusted models.
Comparing the 4th vs the 1st quartile of the omega-3 index confirmed greater hippocampal volume (159 mm3, p=.034).
Conclusion:
A higher omega-3 index was correlated with larger total normal CC & hippocampal volume in post-menopausal women measured 8 yrs later.
Normal aging results in overall brain atrophy, but lower omega-3 index may signal increased risk of hippocampal atrophy.
Future studies should examine: does maintaining higher RBC EPA + DHA levels slow the rate of hippocampal or overall brain atrophy?
Got to remember, as important as DHA is to us right now, as dependent as our brains are on DHA, our ancestors were MORE not less dependent. They lacked our adaptation that helps us to synthesize it. As poor as we are at it, they lacked our ability so
the needed it more in their diet.
OK, thanks a lot, yes, wel possible, but is?was DHA in the diet cause or result? can taking DHA reduce my brain atrophy? what about other spp? what exactly does DHA do in our or other mammals' brains? does the DHA in seafood alone explain Homo's Pleist.
brain enlargement? etc. There are still too many question marks IMO. But it's certainly an argument for more-aquatic ancestors.
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