• vernix caseosa in humans running after antelopes

    From [email protected]@21:1/5 to All on Sat Sep 3 09:21:27 2022
    from [email protected]

    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1

    "Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans."



    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478

    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) and squalene. Vernix particles sloughed
    from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/squalene throughout the gastrointestinal (GI) tract, thereby establishing a unique microbial niche that influences development of nascent microbiota. Here we show
    that late-term California sea lion (Zalophus californianus) fetuses have true vernix caseosa, delivering BCFA and squalene to the fetal GI tract thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the
    production of true vernix caseosa in a species other than Homo sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From DD'eDeN aka note/nickname/alas_my_l@21:1/5 to [email protected] on Sat Sep 3 15:44:35 2022
    On Saturday, September 3, 2022 at 12:21:29 PM UTC-4, [email protected] wrote:
    from [email protected]

    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1

    "Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans."



    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478

    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) and squalene. Vernix particles sloughed
    from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/squalene throughout the gastrointestinal (GI) tract, thereby establishing a unique microbial niche that influences development of nascent microbiota. Here we show
    that late-term California sea lion (Zalophus californianus) fetuses have true vernix caseosa, delivering BCFA and squalene to the fetal GI tract thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the
    production of true vernix caseosa in a species other than Homo sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.
    Localization of double bonds in triacylglycerols using high-performance liquid chromatography/atmospheric pressure chemical ionization ion-trap mass spectrometry
    -

    Czech Academy of Sciences Publication Activity Database

    Háková, Eva; Vrkoslav, Vladimír; Míková, Radka; Schwarzová-Pecková, K.; Bosáková, Z.; Cvačka, Josef

    [Harbor seals and California sea lions have fetal vernix, they are dependent on freshwater in estuaries, they don't live in pure marine coasts.]

    2015-01-01

    Roč. 407, č. 17 (2015), s. 5175-5188 ISSN 1618-2642 R&D Projects: GA ČR GAP206/12/0750 Institutional support: RVO:61388963 Keywords : double bond * gas-phase chemistry * lipidomics * olive oil * vernix caseosa Subject RIV: CB - Analytical
    Chemistry, Separation Impact factor: 3.125, year: 2015

    Branched-chain fatty acids in the neonatal gut and estimated dietary intake in infancy and adulthood.

    Science.gov (United States)

    Ran-Ressler, Rinat R; Glahn, Raymond P; Bae, SangEun; Brenna, J Thomas

    2013-01-01

    Branched-chain fatty acids (BCFA) are primarily saturated fatty acids (FA) with a methyl branch, usually near the terminal methyl group. BCFA are abundant in bacteria, skin, and vernix caseosa but have seldom been studied with respect to human nutrition.
    They are constituents of the term newborn infant gut lumen, being swallowed as vernix particulate components of amniotic fluid in the last trimester of normal pregnancy. We recently showed that BCFA protect against necrotizing enterocolitis (NEC) in the
    rat pup model. Dietary BCFA at levels similar to those found in human vernix reduced NEC incidence by more than 50%, increased the abundance of BCFA-containing bacteria, and increased the expression of ileal anti-inflammatory IL-10. The few published
    reports of BCFA in human milk enable an estimate that breastfed infants consume 19 mg BCFA per 100 ml milk. Dietary BCFA consumption from milk fat and other ruminant products, the main sources of dietary BCFA, is more than 400 mg BCFA per day in adult
    Americans. This estimate exceeds by severalfold the average dietary intake of bioactive FA, such as docosahexaenoic acid. BCFA are bioactive, abundant but neglected components of the human food supply. Copyright © 2013 Nestec Ltd., Vevey/S. Karger AG,
    Basel

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  • From JTEM is so reasonable@21:1/5 to All on Sat Sep 3 21:56:45 2022
    DD'eDeN aka note/nickname/alas_my_loves wrote:

    [...]

    What do you think your "Cite" establishes, and why?

    What do you think it refutes exactly, and why?





    -- --

    https://jtem.tumblr.com/post/694407216559702016

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From [email protected]@21:1/5 to All on Sun Sep 4 00:27:47 2022
    Op zondag 4 september 2022 om 00:44:36 UTC+2 schreef DD'eDeN aka note/nickname/alas_my_loves:

    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1
    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478
    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) & squalene. Vernix particles
    sloughed from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/SQ throughout the gastro-intestinal (GI) tract, establishing a unique microbial niche that influences development of nascent microbiota. Here we show:
    late-term California sea-lion Zalophus californianus fetuses have true vernix caseosa, delivering BCFA & SQ to the fetal GI-tract, thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the production of true
    vernix caseosa in a species other than H.sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.

    Localization of double bonds in triacylglycerols using high-performance liquid chromatography/atmospheric pressure chemical ionization ion-trap mass spectrometry
    [Harbor seals and California sea lions have fetal vernix, they are dependent on freshwater in estuaries, they don't live in pure marine coasts.]

    Nor do we... :-DDD
    Grow up, my little boy.

    Vernix caseosa, flat feet, fat-layer, fur loss, island colonisations, voluntary breathing, huge brain, big nose etc.etc.etc.
    Only incredible imbeciles still deny Pleistocene Homo was primarily coastal. Google "coastal dispersal Pleistocene Homo".

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From [email protected]@21:1/5 to All on Sun Sep 4 00:43:44 2022
    Op zondag 4 september 2022 om 09:27:48 UTC+2 schreef [email protected]:
    Op zondag 4 september 2022 om 00:44:36 UTC+2 schreef DD'eDeN aka note/nickname/alas_my_loves:

    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1
    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478
    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) & squalene. Vernix particles
    sloughed from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/SQ throughout the gastro-intestinal (GI) tract, establishing a unique microbial niche that influences development of nascent microbiota. Here we show:
    late-term California sea-lion Zalophus californianus fetuses have true vernix caseosa, delivering BCFA & SQ to the fetal GI-tract, thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the production of true
    vernix caseosa in a species other than H.sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.
    Localization of double bonds in triacylglycerols using high-performance liquid chromatography/atmospheric pressure chemical ionization ion-trap mass spectrometry
    [Harbor seals and California sea lions have fetal vernix, they are dependent on freshwater in estuaries, they don't live in pure marine coasts.]

    Nor do we... :-DDD
    Grow up, my little boy.
    Vernix caseosa, flat feet, fat-layer, fur loss, island colonisations, voluntary breathing, huge brain, big nose etc.etc.etc.
    Only incredible imbeciles still deny Pleistocene Homo was primarily coastal. Google "coastal dispersal Pleistocene Homo".

    I forgot the most important: H.erectus was pachyosteosclerotic (POS):
    very thick & dense cortical bone, facilitating diving, and seen in all slow+shallow diving tetrapods, and nowhere else.
    Early Pinnipedia & Cetacea were also POS. Only later most of them evolved lightly-built skeletons, for fast & deep diving.
    Only incredible idiots deny H.erectus frequently dived (likely initially in salt water (denser), probably mostly for shellfish cf. stone tools).

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From DD'eDeN aka note/nickname/alas_my_l@21:1/5 to [email protected] on Mon Sep 5 00:01:03 2022
    On Sunday, September 4, 2022 at 3:43:45 AM UTC-4, [email protected] wrote:
    Op zondag 4 september 2022 om 09:27:48 UTC+2 schreef [email protected]:
    Op zondag 4 september 2022 om 00:44:36 UTC+2 schreef DD'eDeN aka note/nickname/alas_my_loves:

    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1
    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478
    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) & squalene. Vernix particles
    sloughed from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/SQ throughout the gastro-intestinal (GI) tract, establishing a unique microbial niche that influences development of nascent microbiota. Here we show:
    late-term California sea-lion Zalophus californianus fetuses have true vernix caseosa, delivering BCFA & SQ to the fetal GI-tract, thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the production of true
    vernix caseosa in a species other than H.sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.
    Localization of double bonds in triacylglycerols using high-performance liquid chromatography/atmospheric pressure chemical ionization ion-trap mass spectrometry
    [Harbor seals and California sea lions have fetal vernix, they are dependent on freshwater in estuaries, they don't live in pure marine coasts.]

    Nor do we... :-DDD
    Grow up, my little boy.
    Vernix caseosa, flat feet, fat-layer, fur loss, island colonisations, voluntary breathing, huge brain, big nose etc.etc.etc.
    Only incredible imbeciles still deny Pleistocene Homo was primarily coastal.
    Google "coastal dispersal Pleistocene Homo".
    I forgot the most important:

    Yes, your alzheimers/selective amnesia is raging again. Take your meds & sleep in your shelter..

    H.erectus was pachyosteosclerotic (POS):
    very thick & dense cortical bone, facilitating diving, and seen in all slow+shallow diving tetrapods, and nowhere else.
    Early Pinnipedia & Cetacea were also POS. Only later most of them evolved lightly-built skeletons, for fast & deep diving.
    Only incredible idiots deny H.erectus frequently dived (likely initially in salt water (denser), probably mostly for shellfish cf. stone tools).

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From DD'eDeN aka note/nickname/alas_my_l@21:1/5 to [email protected] on Sun Sep 4 23:59:04 2022
    On Sunday, September 4, 2022 at 3:27:48 AM UTC-4, [email protected] wrote:
    Op zondag 4 september 2022 om 00:44:36 UTC+2 schreef DD'eDeN aka note/nickname/alas_my_loves:
    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1
    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478
    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) & squalene. Vernix particles
    sloughed from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/SQ throughout the gastro-intestinal (GI) tract, establishing a unique microbial niche that influences development of nascent microbiota. Here we show:
    late-term California sea-lion Zalophus californianus fetuses have true vernix caseosa, delivering BCFA & SQ to the fetal GI-tract, thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the production of true
    vernix caseosa in a species other than H.sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.
    Localization of double bonds in triacylglycerols using high-performance liquid chromatography/atmospheric pressure chemical ionization ion-trap mass spectrometry
    [Harbor seals and California sea lions have fetal vernix, they are dependent on freshwater in estuaries, they don't live in pure marine coasts.]
    Nor do we.

    So irrelevant, no marine, no marine chimp.

    .. :-DDD
    Grow up, my little boy.

    Vernix caseosa, flat feet, fat-layer, fur loss, island colonisations, voluntary breathing, huge brain, big nose etc.etc.etc.
    Only incredible imbeciles still deny Pleistocene Homo was primarily coastal. Google "coastal dispersal Pleistocene Homo".

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From [email protected]@21:1/5 to All on Mon Sep 5 04:14:18 2022
    Typical endurance runner's "argument":

    Yes, your alzheimers/selective amnesia is raging again. Take your meds & sleep in your shelter..

    H.erectus was pachyosteosclerotic (POS):
    very thick & dense cortical bone, facilitating diving, and seen in all slow+shallow diving tetrapods, and nowhere else.
    Early Pinnipedia & Cetacea were also POS. Only later most of them evolved lightly-built skeletons, for fast & deep diving.
    Only incredible idiots deny H.erectus frequently dived (likely initially in salt water (denser), probably mostly for shellfish cf. stone tools).

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From [email protected]@21:1/5 to All on Thu Sep 8 09:25:47 2022
    Op maandag 5 september 2022 om 09:01:05 UTC+2 schreef DD'eDeN aka note/nickname/alas_my_loves:


    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1
    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478
    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) & squalene. Vernix particles
    sloughed from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/SQ throughout the gastro-intestinal (GI) tract, establishing a unique microbial niche that influences development of nascent microbiota. Here we show:
    late-term California sea-lion Zalophus californianus fetuses have true vernix caseosa, delivering BCFA & SQ to the fetal GI-tract, thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the production of true
    vernix caseosa in a species other than H.sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.
    Localization of double bonds in triacylglycerols using high-performance liquid chromatography/atmospheric pressure chemical ionization ion-trap mass spectrometry
    [Harbor seals and California sea lions have fetal vernix, they are dependent on freshwater in estuaries, they don't live in pure marine coasts.]

    Nor do we... :-DDD
    Grow up, my little boy.
    Vernix caseosa, flat feet, fat-layer, fur loss, island colonisations, voluntary breathing, huge brain, big nose etc.etc.etc.
    Only incredible imbeciles still deny Pleistocene Homo was primarily coastal.
    Google "coastal dispersal Pleistocene Homo".

    I forgot the most important:

    Yes, your alzheimers/selective amnesia is raging again. Take your meds & sleep in your shelter..

    H.erectus was pachyosteosclerotic (POS):
    very thick & dense cortical bone, facilitating diving, and seen in all slow+shallow diving tetrapods, and nowhere else.
    Early Pinnipedia & Cetacea were also POS. Only later most of them evolved lightly-built skeletons, for fast & deep diving.
    Only incredible idiots deny H.erectus frequently dived (likely initially in salt water (denser), probably mostly for shellfish cf. stone tools).

    https://www.researchgate.net/publication/323832499_Coastal_Dispersal_of_Pleistocene_Homo

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)
  • From DD'eDeN aka note/nickname/alas_my_l@21:1/5 to [email protected] on Thu Sep 8 13:48:35 2022
    On Saturday, September 3, 2022 at 12:21:29 PM UTC-4, [email protected] wrote:
    from [email protected]

    They've now found that Sea lions also have vernix https://www.nature.com/articles/s41598-018-25871-1

    "Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans."



    Sea Lions Develop Human-like Vernix Caseosa Delivering Branched Fats and Squalene to the GI Tract
    Dong Hao Wang cs 2018 Scientific Reports 8, 7478

    Vernix caseosa, the white waxy coating found on newborn human skin, is thought to be a uniquely human substance. Its signature characteristic is exceptional richness in saturated branched chain fatty acids (BCFA) and squalene. Vernix particles sloughed
    from the skin suspended in amniotic fluid are swallowed by the human fetus, depositing BCFA/squalene throughout the gastrointestinal (GI) tract, thereby establishing a unique microbial niche that influences development of nascent microbiota. Here we show
    that late-term California sea lion (Zalophus californianus) fetuses have true vernix caseosa, delivering BCFA and squalene to the fetal GI tract thereby recapitulating the human fetal gut microbial niche. These are the first data demonstrating the
    production of true vernix caseosa in a species other than Homo sapiens. Its presence in a marine mammal supports the hypothesis of an aquatic habituation period in the evolution of modern humans.

    Squalene Found in Alpine Grassland Soils under a Harsh Environment in the Tibetan Plateau, China
    https://www.mdpi.com/2218-273X/8/4/154/htm

    Also found in tropical forest soils & fauna.

    California sea lions have dense fur coat; Homo never had that, being sheltered, so probably coincidental. Semi-aquatic, littoral and aquamarine fauna do not have vernix.

    --- SoupGate-Win32 v1.05
    * Origin: fsxNet Usenet Gateway (21:1/5)