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Psilocybin’s main effects is to stimulate a serotonin receptor called “5-HT2A” located in the prefrontal cortex, which leads to two important results:
The production of “Brain-Derived Neurotrophic Factor” (BDNF), a protein that is “like Miracle-Gro for your brain,” according to Waldman. BDNF stimulates growth, connections, and activity. [1]
The increased transmission of “Glutamate,” a neurotransmitter responsible (in part) for important brain functions such as cognition, learning, and memory. [2]
Dampen the activity of an often over-used part of our brain called the “Default Mode Network” (DMN). [4] The DMN is responsible for many mental activities, including day-dreaming, self-reflection, and thinking about the past or the future
Psychedelics could be used to combat depression and anxiety—as well as lead to insights and creative perspectives that may otherwise remain inaccessible.
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