• WHO sets a standard

    From ScottW@21:1/5 to All on Wed Jan 25 20:19:45 2023
    and the Vaxx comes up short.

    But the findings mean the bivalent shots - which the US Government paid $5billion for last autumn - fall short of the World Health Organization's 50 percent efficacy threshold for an effective vaccine.

    ScottW

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  • From mINE109@21:1/5 to ScottW on Thu Jan 26 09:35:04 2023
    On 1/25/23 10:19 PM, ScottW wrote:
    and the Vaxx comes up short.

    But the findings mean the bivalent shots - which the US Government
    paid $5billion for last autumn - fall short of the World Health Organization's 50 percent efficacy threshold for an effective
    vaccine.

    Without citations, your claims aren't falsifiable. My guess is you
    misread something like "boosters 25% more effective than previous
    vaccination" as "boosters 25% effective."

    https://www.nejm.org/doi/full/10.1056/NEJMc2215471

    "For all participants 12 years of age or older, vaccine effectiveness
    against severe infection resulting in hospitalization over days 15 to 99
    after receipt of one monovalent booster dose was 25.2% (95% confidence
    interval [CI], –0.2 to 44.2), and the corresponding vaccine
    effectiveness for one bivalent booster dose was 58.7% (95% CI, 43.7 to
    69.8)"

    tl/dr: boosters more effective than original vaccine

    or 58 > 50

    From the conclusion:

    Bivalent boosters provided substantial additional protection against
    severe omicron infection in persons who had previously been vaccinated
    or boosted, although the effectiveness waned over time. The
    effectiveness of bivalent boosters was higher than that of monovalent
    boosters.

    We adjusted for measured confounders, including vaccination history,
    previous infection, and demographic variables. However, estimates of
    booster effectiveness would be biased if boosted persons were more
    likely or less likely to seek Covid-19 testing than nonboosted persons.
    For this reason, we focused on severe infection, which was more likely
    to be reported than mild infection. Very strong unmeasured confounders
    would be required in order to fully explain away the observed
    effectiveness of bivalent boosters.

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  • From ScottW@21:1/5 to All on Thu Jan 26 16:41:27 2023
    On Thursday, January 26, 2023 at 7:59:38 AM UTC-8, MINe109 wrote:
    On 1/25/23 10:19 PM, ScottW wrote:
    and the Vaxx comes up short.

    But the findings mean the bivalent shots - which the US Government
    paid $5billion for last autumn - fall short of the World Health Organization's 50 percent efficacy threshold for an effective
    vaccine.
    Without citations, your claims aren't falsifiable.

    https://www.dailymail.co.uk/health/article-11677059/CDC-study-finds-bivalent-Covid-vaccines-provide-strong-protection-against-XBB-1-5-variant.html

    A report by the Centers for Disease Control and Prevention (CDC) released Wednesday found the updated shots were just 48 percent effective at stopping symptomatic infection caused by the XBB.1.5 subvariant for up to three months.

    But the CDC decided to redefine the purpose of a vaccine.

    The CDC highlighted that the main purpose of the vaccines is to prevent hospitalization and death rather than transmission.

    So just for the comorbid and uber paranoid like Stephen.

    ScottW

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  • From mINE109@21:1/5 to ScottW on Fri Jan 27 09:40:25 2023
    On 1/26/23 6:41 PM, ScottW wrote:
    On Thursday, January 26, 2023 at 7:59:38 AM UTC-8, MINe109 wrote:
    On 1/25/23 10:19 PM, ScottW wrote:
    and the Vaxx comes up short.

    But the findings mean the bivalent shots - which the US
    Government paid $5billion for last autumn - fall short of the
    World Health Organization's 50 percent efficacy threshold for an
    effective vaccine.
    Without citations, your claims aren't falsifiable.

    https://www.dailymail.co.uk/health/article-11677059/CDC-study-finds-bivalent-Covid-vaccines-provide-strong-protection-against-XBB-1-5-variant.html

    A report by the Centers for Disease Control and Prevention (CDC)
    released Wednesday found the updated shots were just 48 percent
    effective at stopping symptomatic infection caused by the XBB.1.5
    subvariant for up to three months.

    Yes, a misreading to get from "provide strong protection" to "comes up
    short."

    But the CDC decided to redefine the purpose of a vaccine.

    The CDC highlighted that the main purpose of the vaccines is to
    prevent hospitalization and death rather than transmission.

    So just for the comorbid and uber paranoid like Stephen.

    The WHO:

    A vaccine’s efficacy is measured in a controlled clinical trial and is
    based on how many people who got vaccinated developed the ‘outcome of interest’ (usually disease) compared with how many people who got the
    placebo (dummy vaccine) developed the same outcome. Once the study is
    complete, the numbers of sick people in each group are compared, in
    order to calculate the relative risk of getting sick depending on
    whether or not the subjects received the vaccine. From this we get the
    efficacy – a measure of how much the vaccine lowered the risk of getting sick. If a vaccine has high efficacy, a lot fewer people in the group
    who received the vaccine got sick than the people in the group who
    received the placebo.

    End quote.

    Two-fold less death compared to unboosted and thirteen-fold compared to
    unvaxed looks effective enough. If your infection is asymptomatic, are
    you sick?

    If you want to argue current vaccines aren't effective enough against
    spread of COVID, we agree and you'll join me in calling for
    non-pharmaceutical interventions, especially easy to achieve measures
    such as improved ventilation, filtering (both mechanical and UV), and
    masking where appropriate (indoor gatherings, etc).

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  • From ScottW@21:1/5 to All on Fri Jan 27 17:14:38 2023
    On Friday, January 27, 2023 at 7:40:27 AM UTC-8, MINe109 wrote:
    On 1/26/23 6:41 PM, ScottW wrote:
    On Thursday, January 26, 2023 at 7:59:38 AM UTC-8, MINe109 wrote:
    On 1/25/23 10:19 PM, ScottW wrote:
    and the Vaxx comes up short.

    But the findings mean the bivalent shots - which the US
    Government paid $5billion for last autumn - fall short of the
    World Health Organization's 50 percent efficacy threshold for an
    effective vaccine.
    Without citations, your claims aren't falsifiable.

    https://www.dailymail.co.uk/health/article-11677059/CDC-study-finds-bivalent-Covid-vaccines-provide-strong-protection-against-XBB-1-5-variant.html

    A report by the Centers for Disease Control and Prevention (CDC)
    released Wednesday found the updated shots were just 48 percent
    effective at stopping symptomatic infection caused by the XBB.1.5 subvariant for up to three months.
    Yes, a misreading to get from "provide strong protection" to "comes up short."

    Your subjective BS assessment of strong vs a documented and quantifiable
    WHO metric.

    You lose.

    ScottW

    --- SoupGate-Win32 v1.05
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  • From mINE109@21:1/5 to ScottW on Sat Jan 28 09:41:35 2023
    On 1/27/23 7:14 PM, ScottW wrote:
    On Friday, January 27, 2023 at 7:40:27 AM UTC-8, MINe109 wrote:
    On 1/26/23 6:41 PM, ScottW wrote:
    On Thursday, January 26, 2023 at 7:59:38 AM UTC-8, MINe109 wrote:
    On 1/25/23 10:19 PM, ScottW wrote:
    and the Vaxx comes up short.

    But the findings mean the bivalent shots - which the US
    Government paid $5billion for last autumn - fall short of the
    World Health Organization's 50 percent efficacy threshold for an
    effective vaccine.
    Without citations, your claims aren't falsifiable.

    https://www.dailymail.co.uk/health/article-11677059/CDC-study-finds-bivalent-Covid-vaccines-provide-strong-protection-against-XBB-1-5-variant.html

    A report by the Centers for Disease Control and Prevention (CDC)
    released Wednesday found the updated shots were just 48 percent
    effective at stopping symptomatic infection caused by the XBB.1.5
    subvariant for up to three months.
    Yes, a misreading to get from "provide strong protection" to "comes up
    short."

    Your subjective BS assessment of strong vs a documented and quantifiable
    WHO metric.

    It's in the URL. Thank the Daily Mail.

    You lose.

    My quote is accurate. The CDC:

    "Vaccine effectiveness is a measure of how well vaccination protects
    people against outcomes such as infection, symptomatic illness, hospitalization, and death. Vaccine effectiveness is typically measured
    through observational studies specifically designed to estimate
    individual protection from vaccination under “real-world” conditions."

    The Daily Mail chose a scary "MAJORITY...not protected" frame to
    characterize 48% effectiveness against spread and much higher protection against serious illness and death.

    It might also be mentioned the boosters were developed for older strains
    of COVID and the newer XBB was at one time considered 'most vaccine
    resistant strain ever'.

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