XPost: linux.debian.devel
Package: wnpp
Severity: wishlist
Owner: Steffen Moeller <
[email protected]>
X-Debbugs-Cc:
[email protected],
[email protected]
* Package name : python-isovar
Version : 0.7.0
* URL :
https://github.com/openvax/isovar
* License : Apache-2.0
Programming Lang: Python
Description : determines mutant protein subsequences around mutations from cancer RNAseq data
Isovar determines mutant protein subsequences around mutations from
cancer RNAseq data.
.
Isovar works by:
* collecting RNA reads which spanning the location of a variant,
* filtering the RNA reads to those which support the mutation,
* assembling mutant reads into longer coding sequences,
* matching mutant coding sequences against reference annotated reading
frames, and
* translating coding sequences determined directly from RNA into
* mutant
protein sequences.
.
The assembled coding sequences may incorporate proximal (germline and
somatic) variants, along with any splicing alterations which occur due
to modified splice signals.
The project will be team-maintained at
https://salsa.debian.org/med-team/python-isovar .
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